mitochondria targeted antioxidant agent (mito tempo) Search Results


mitochondria-targeted antioxidant, mito-tempo  (Enzo Biochem)
90
Enzo Biochem mitochondria-targeted antioxidant, mito-tempo
Mitochondrial H2O2 elicits apoptosis in rotenone-exposed neuronal cells. The indicated cells were treated with (A and B) rotenone (0.5 and 1 μM) in the presence or absence of TTFA (10 μM) or antimycin A (50 μM) for 24 h, or (C, D, E, and F) pretreated with/without <t>Mito-TEMPO</t> (10 μM) for 1 h and then exposed to rotenone (0.5 and 1 μM) for 24 h, followed by (A, B, and C) H2O2 imaging using a peroxide-selective probe H2DCFDA, (D) cell viability evaluation using the MTS assay, (E) cell apoptosis analysis using DAPI staining, or (F) Western blotting using the indicated antibodies. For (F), the blots were probed for β-tubulin as a loading control. Similar results were observed in at least three independent experiments. For (A), (B), (C), (D), and (E), all data were expressed as means ± SEM (n = 6). ap < .05, difference with control group; b p < .05, difference with 0.5 μM rotenone group; cp < .05, difference with 1 μM rotenone group.
Mitochondria Targeted Antioxidant, Mito Tempo, supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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mitochondria-targeted antioxidant, mito-tempo - by Bioz Stars, 2026-02
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mitochondria-targeted antioxidants mta-mito tempo  (MitoQ Ltd)
90
MitoQ Ltd mitochondria-targeted antioxidants mta-mito tempo
Mitochondrial H2O2 elicits apoptosis in rotenone-exposed neuronal cells. The indicated cells were treated with (A and B) rotenone (0.5 and 1 μM) in the presence or absence of TTFA (10 μM) or antimycin A (50 μM) for 24 h, or (C, D, E, and F) pretreated with/without <t>Mito-TEMPO</t> (10 μM) for 1 h and then exposed to rotenone (0.5 and 1 μM) for 24 h, followed by (A, B, and C) H2O2 imaging using a peroxide-selective probe H2DCFDA, (D) cell viability evaluation using the MTS assay, (E) cell apoptosis analysis using DAPI staining, or (F) Western blotting using the indicated antibodies. For (F), the blots were probed for β-tubulin as a loading control. Similar results were observed in at least three independent experiments. For (A), (B), (C), (D), and (E), all data were expressed as means ± SEM (n = 6). ap < .05, difference with control group; b p < .05, difference with 0.5 μM rotenone group; cp < .05, difference with 1 μM rotenone group.
Mitochondria Targeted Antioxidants Mta Mito Tempo, supplied by MitoQ Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/mitochondria-targeted antioxidants mta-mito tempo/product/MitoQ Ltd
Average 90 stars, based on 1 article reviews
mitochondria-targeted antioxidants mta-mito tempo - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier

Image Search Results


Mitochondrial H2O2 elicits apoptosis in rotenone-exposed neuronal cells. The indicated cells were treated with (A and B) rotenone (0.5 and 1 μM) in the presence or absence of TTFA (10 μM) or antimycin A (50 μM) for 24 h, or (C, D, E, and F) pretreated with/without Mito-TEMPO (10 μM) for 1 h and then exposed to rotenone (0.5 and 1 μM) for 24 h, followed by (A, B, and C) H2O2 imaging using a peroxide-selective probe H2DCFDA, (D) cell viability evaluation using the MTS assay, (E) cell apoptosis analysis using DAPI staining, or (F) Western blotting using the indicated antibodies. For (F), the blots were probed for β-tubulin as a loading control. Similar results were observed in at least three independent experiments. For (A), (B), (C), (D), and (E), all data were expressed as means ± SEM (n = 6). ap < .05, difference with control group; b p < .05, difference with 0.5 μM rotenone group; cp < .05, difference with 1 μM rotenone group.

Journal: Toxicological Sciences

Article Title: Rotenone Induction of Hydrogen Peroxide Inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E Pathways, Leading to Neuronal Apoptosis

doi: 10.1093/toxsci/kfu211

Figure Lengend Snippet: Mitochondrial H2O2 elicits apoptosis in rotenone-exposed neuronal cells. The indicated cells were treated with (A and B) rotenone (0.5 and 1 μM) in the presence or absence of TTFA (10 μM) or antimycin A (50 μM) for 24 h, or (C, D, E, and F) pretreated with/without Mito-TEMPO (10 μM) for 1 h and then exposed to rotenone (0.5 and 1 μM) for 24 h, followed by (A, B, and C) H2O2 imaging using a peroxide-selective probe H2DCFDA, (D) cell viability evaluation using the MTS assay, (E) cell apoptosis analysis using DAPI staining, or (F) Western blotting using the indicated antibodies. For (F), the blots were probed for β-tubulin as a loading control. Similar results were observed in at least three independent experiments. For (A), (B), (C), (D), and (E), all data were expressed as means ± SEM (n = 6). ap < .05, difference with control group; b p < .05, difference with 0.5 μM rotenone group; cp < .05, difference with 1 μM rotenone group.

Article Snippet: Mitochondria-targeted antioxidant, Mito-TEMPO and the pan-caspase inhibitor, z-Val-Ala-Asp-CH 2 F (zVAD-fmk) were acquired from ALEXIS Biochemicals Corporation (San Diego, CA).

Techniques: Imaging, MTS Assay, Staining, Western Blot